An Allergist-immunologist is an Internal Medicine, or for children - a Pediatric, medical doctor with additional qualifications enabling specialization in the evaluation and management of disorders involving sensitive response states of the immune system. Allergist-immunologists manage adverse reactions to drugs, foods, insect stings and other environmental agents. These reactions may vary in severity and include rhinitis (runny nose and sneezing), eczema and other skin reactions, asthma and even life threatening anaphylaxis. Allergist-immunologists also manage weakened immune deficiency diseases both acquired and congenital and they treat autoimmune diseases such as lupus or scleroderma. And finally, these specialists manage immune rejection issues related to organ transplantation and malignancies of the immune system.